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Antifungal activity of n-tributyltin acetate against some common yam rot fungi
P F Olurinola1, J O Ehinmidu, J J Bonire
1Department of Pharmaceutics and Pharmaceutical Microbiology, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Nigeria.
Applied and Environmental Microbiology
|February 1, 1992
Abstract:
The antifungal activity of n-tributyltin acetate (TBTA) was examined in relation to combating yam rot disease. TBTA exhibited a significant effect in vitro and in vivo on four yam rot fungal isolates tested. However, the in vitro toxicity of TBTA was drastically reduced when 2.5% Tween 80 was the solvent instead of 25% acetone, as indicated by the MICs of 156.0 and 5.0 micrograms/ml, respectively.