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Bilateral internal jugular vein thrombosis in a child with protein S deficiency

S Gunasekaran1, R Anthony, C J Woodhead

  • 1Department of Otolaryngology, Leeds General Infirmary, Leeds, UK. gunasek98@yahoo.com

The Journal of Laryngology and Otology
|August 17, 2005
PubMed

Insights

Bilateral internal jugular vein thrombosis is rare in children. A 14-year-old girl with protein S deficiency developed this condition with severe complications, a case previously unreported.

Area of Science:

  • Vascular Medicine
  • Pediatric Thrombosis
  • Genetics and Thrombophilia

Background:

  • Internal jugular vein thrombosis (IJVT) is a rare condition, predominantly reported in adults.
  • Iatrogenic trauma is the most common cause of IJVT, with limited literature on pediatric cases.

Observation:

  • A 14-year-old female presented with bilateral internal jugular venous thrombosis.
  • The patient had a diagnosed deficiency in protein S, a known risk factor for thrombosis.

Findings:

  • The case involved bilateral IJVT, a presentation not previously documented in the pediatric population.
  • The patient experienced significant pulmonary and cerebral complications secondary to the thrombosis.

Implications:

  • This case highlights the potential for severe IJVT in pediatric patients with thrombophilia, such as protein S deficiency.
  • It underscores the need for increased awareness and consideration of IJVT in children presenting with relevant risk factors and symptoms.
  • Further research into pediatric IJVT, particularly in the context of inherited thrombophilias, is warranted.

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