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Updated: Aug 16, 2026

Controlled Microfluidic Environment for Dynamic Investigation of Red Blood Cell Aggregation
Published on: June 4, 2015
[Development of the chip system for measurement of red blood cell rheology]
Yan-jian Liao1, Xiao-lin Zheng, Wen-xian Zhang
1The Key Laboratory, the Education Ministry of Biodynamics and Organism Engineering, The College of Bioengineering, Chongqing University.
Abstract:
We have developed a novel silicon microchannel system for the research of the red blood cell rheology and deformation. Recurring to many kinds of information technologies and advanced test means such as the electronic microscope, the image acquisition system and the computer processing system and by using the up-to-date Micro Electro Mechanical System (MEMS) technology, a new measuring system of red bood cell deformation is designed based on the chip and a model using the silicon microchannel to simulate capillary vessel network. It provides a real-time collection and anaysis of data which include image, speed, flow parameter, and so on. It provides printing, storage of the analysis results and patients' database management.

