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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

Cardiac surgery in patients on antiplatelet and antithrombotic agents

Y Joseph Woo1

  • 1Minimally Invasive and Robotic Cardiac Surgery Program, Division of Cardiothoracic Surgery, Department of Surgery, University of Pennsylvania, Silverstein 6, 3400 Spruce Street, Philadelphia, PA 19104, USA. wooy@uphs.upenn.edu

Seminars in Thoracic and Cardiovascular Surgery
|August 18, 2005
PubMed

Insights

Antithrombotic agents increase bleeding risk in cardiac surgery. This review details strategies to manage peri-operative hemorrhage, focusing on both medications and surgical techniques.

Area of Science:

  • Cardiovascular Surgery
  • Anesthesiology
  • Pharmacology

Background:

  • Antithrombotic agents are crucial for preventing thrombosis but increase bleeding risks.
  • Peri-operative hemorrhage is a significant complication in cardiac surgery.
  • Managing bleeding while maintaining therapeutic antithrombotic effects is challenging.

Purpose of the Study:

  • To review antithrombotic agents used in cardiac surgery.
  • To discuss strategies for attenuating peri-operative hemorrhage.
  • To provide an in-depth overview of anti-hemorrhagic measures.

Main Methods:

  • Literature review of antithrombotic agents.
  • Analysis of surgical techniques for bleeding control.
  • Review of medical strategies for hemorrhage management.

Main Results:

  • Identification of key antithrombotic agents and their bleeding risks.
  • Summary of effective surgical interventions to reduce blood loss.
  • Overview of pharmacological and non-pharmacological anti-hemorrhagic measures.

Conclusions:

  • Effective management of peri-operative hemorrhage in cardiac surgery requires a multi-faceted approach.
  • Balancing antithrombotic therapy with bleeding risk is essential.
  • Specific strategies can significantly attenuate bleeding complications.

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