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Related Experiment Videos

First-trimester risk assessment: twin gestations.

Lawrence D Platt1

  • 1Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, and Center for Fetal Medicine and Women's Ultrasound, Los Angeles, CA 90048, USA. LPlatt8496@aol.com

Seminars in Perinatology
|August 18, 2005
PubMed
Summary

First-trimester screening for multiple gestations shows promise, but detection rates for twins are lower than for singletons. Further research is needed to optimize screening methods for twin pregnancies.

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Area of Science:

  • Maternal-fetal medicine
  • Prenatal diagnostics

Background:

  • First-trimester screening is crucial for assessing fetal aneuploidy risk.
  • Most existing research focuses on singleton pregnancies, leaving a gap in understanding its application in multiple gestations.

Purpose of the Study:

  • To evaluate the efficacy and role of first-trimester screening in multiple gestations.
  • To compare screening performance between singleton and multiple pregnancies.

Main Methods:

  • A comprehensive literature review was conducted.
  • Studies specifically examining first-trimester screening in multiple gestations were analyzed.

Main Results:

  • First-trimester screening in multiple gestations is feasible.

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  • The detection rate for twin gestations was found to be lower compared to singleton gestations.

    • Conclusions:

    • First-trimester biochemical and ultrasound screening is valuable for twin pregnancies.
    • Additional research is required to identify the most sensitive screening methods for multiple gestations.