Is there an association between periodontal disease, prematurity and low birth weight? A population-based study

Abelardo Nunes Lunardelli1, Marco Aurélio Peres

  • 1Departamento de Saúde Pública, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, Florianópolis, Brazil.

Insights

This study found no link between maternal periodontal disease and low birth weight. While prematurity showed a temporary association with periodontal pockets, this connection was ultimately explained by other maternal health factors.

Area of Science:

  • Obstetrics and Gynecology
  • Periodontology
  • Public Health

Background:

  • The connection between pregnancy periodontal disease and adverse birth outcomes like low birth weight and prematurity remains unclear.
  • Existing research presents conflicting findings, necessitating further investigation.

Purpose of the Study:

  • To investigate the association between periodontal disease in pregnant women and the incidence of low birth weight or preterm birth.
  • To clarify the relationship between maternal periodontal health and infant birth outcomes.

Main Methods:

  • A population-based, cross-sectional study involving 449 parturients in Southern Brazil.
  • Data collected via interviews, clinical examinations (identifying periodontal pockets), questionnaires, and medical records.
  • Statistical analysis included simple and multiple regression to assess associations.

Main Results:

  • No statistically significant association was observed between periodontal disease and low birth weight.
  • An initial association between periodontal pockets and prematurity was identified (OR=2.6).
  • This association with prematurity disappeared after adjusting for maternal health variables, indicating confounding.

Conclusions:

  • Maternal periodontal disease is not associated with low birth weight in offspring.
  • While a link between periodontal pockets and prematurity was initially suggested, it was confounded by maternal health factors, negating a direct causal relationship.
Abstract

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