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A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
[Diabetes mellitus in children]
1Semmelweis Egyetem, Altalános Orvostudományi Kar, I. Gyermekklinika, Budapest.
Insights
This review covers childhood diabetes, focusing on type 1 diabetes diagnostics, management, and etiology. It also addresses the rising incidence of type 2 diabetes in children linked to obesity.
Area of Science:
- Pediatric Endocrinology
- Metabolic Disorders
Background:
- Diabetes mellitus in children and adolescents presents unique challenges due to ongoing growth and development.
- Type 1 diabetes is the predominant form in the pediatric population.
- Increasing childhood obesity rates correlate with a rise in type 2 diabetes in this age group.
Purpose of the Study:
- To provide a comprehensive overview of various forms of diabetes mellitus in children and adolescents.
- To detail the diagnostics, epidemiology, etiopathogenesis, and natural course of type 1 diabetes.
- To discuss management strategies and other carbohydrate intolerances in pediatric populations.
Main Methods:
- Review of existing literature on pediatric diabetes.
- Analysis of diagnostic criteria and epidemiological data.
- Synthesis of information on etiopathogenesis and treatment modalities.
Main Results:
- Type 1 diabetes characteristics, diagnostics, and management (insulin therapy, nutrition, education) are detailed.
- The review highlights the increasing prevalence of type 2 diabetes in children and adolescents.
- Other forms of carbohydrate intolerance are also considered.
Conclusions:
- Effective management of childhood diabetes requires age-specific approaches.
- Understanding the distinct etiopathogenesis of type 1 and type 2 diabetes is crucial for pediatric care.
- Addressing the rising incidence of type 2 diabetes, particularly in relation to obesity, is a key public health concern.
Abstract:
The review is covering different forms of diabetes mellitus occurring in children and adolescents. Main characteristics of childhood diabetes are based on the continuous changes in growth and development of children. The review is focusing on the diagnostics, epidemiology, etiopathogenesis and natural course of type 1 diabetes, the dominant form in the pediatric age group. Insulin treatment, nutritional management and education, including age related special problems are covered. Due to space limitations, acute and late complications, as well as possible prevention of type 1 diabetes are shortly mentioned. Beside type 1 diabetes, other forms of carbohydrate intolerance occurring in children are also also included. Among those, special emphasis is put on type 2 diabetes, due to its increasing incidence in children and adolescents parallel to the increased prevalence of childhood obesity.
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