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Updated: Jul 31, 2026

05:06
A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
Published on: October 24, 2015
Amoebic liver abscess imitating metastatic caecal carcinoma
Jan Ritchie1, Adam Harper, Vladimir Malykh
1Department of Medicine for Older People, Queen Alexandra Hospital, Portsmouth, UK. jan.ritchie@btopenworld.com
Age and Ageing
|August 19, 2005
Summary
A patient initially diagnosed with incurable cancer was found to have a treatable infection. This case highlights the importance of considering rare infections in differential diagnoses for poor-prognosis conditions.
Area of Science:
- Medical Case Study
- Infectious Diseases
- Oncology
Background:
- Initial patient investigations indicated a grim prognosis, suggesting an advanced, incurable carcinoma.
- The diagnostic challenge involved differentiating between malignant disease and other severe conditions.
Observation:
- The patient presented with symptoms initially indicative of a terminal cancer diagnosis.
- Subsequent diagnostic procedures revealed an unexpected etiology for the observed clinical picture.
Findings:
- The presumed carcinoma was ultimately identified as an unusual, yet curable, infectious disease.
- This misdiagnosis underscores the complexity of clinical presentations and diagnostic pathways.
Implications:
- This case emphasizes the critical need for comprehensive differential diagnoses, including rare infections, in oncology.
- It highlights the potential for successful treatment outcomes when challenging diagnoses are accurately identified.
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