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[Gestational trophoblastic diseases: a retrospective study from 1997 to 2003]
Background:
Trophoblastic diseases correspond to a very heterogeneous group of rare pathology in young women which fertility should be preserved.
Patient And Methods:
We conducted a retrospective study from 1997 to 2003, including all patients with molar pregnancy or trophoblatic tumor in our department of Obstetrics and Gynecology.
Results:
Fifteen patients were identified with 9 molar pregnancies, 5 trophoblastic tumors and 1 placental tumor of implantation site. The outcome was favorable for 14, and one patient died from her metastatic disease. For 4 patients we asked our university colleague for the optimal approach.
Discussion:
Management of molar pregnancies is well established. Persistent gestational disease is more rare and problematic with potential metastatic dissemination. Multidisciplinary care is often needed.
Conclusion:
Persistent gestational disease should be managed in a highly specialized centre, as developed in the Lyon University Hospital.
