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[Gastroesophageal reflux in asthmatic children: prevalence and pathogenic role]

Dorin Farcău1, Daniela Dreghiciu, Paraschiva Cherecheş-Panţa

  • 1Clinica Pediatrie III- UMF "Iuliu Haţieganu", Cluj-Napoca, România.

Pneumologia (Bucharest, Romania)
|August 20, 2005
PubMed

Insights

Gastroesophageal reflux disease is common in children with asthma, affecting lung function. This study found a strong link between reflux severity and reduced pulmonary function in pediatric asthma patients.

Area of Science:

  • Pediatric Pulmonology
  • Gastroenterology

Context:

  • The link between asthma and gastroesophageal reflux disease (GERD) is debated.
  • Asthma management in children requires understanding contributing factors.

Purpose:

  • To determine the prevalence of pathologic gastroesophageal reflux in children with asthma.
  • To evaluate the impact of gastroesophageal reflux on pulmonary function tests in this population.

Summary:

  • A study of 34 asthmatic children (ages 2.5-17) utilized 24-hour esophageal pH monitoring and spirometry.
  • Results indicated an 87% prevalence of pathologic gastroesophageal reflux.
  • A significant inverse correlation (r = -0.67) was observed between reflux severity and the FEV1/FVC ratio.

Impact:

  • This research highlights a high prevalence of gastroesophageal reflux in pediatric asthma.
  • Findings suggest that gastroesophageal reflux contributes to the severity of asthma in children.

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