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Encapsulating peritoneal sclerosis in paediatric peritoneal dialysis patients
Mesiha Ekim1, Suat Fitöz, Aydin Yagmurlu
1Department of Paediatric Nephrology, School of Medicine, Ankara University, Ankara, Turkey. ekim@medicine.ankara.edu.tr
Nephrology (Carlton, Vic.)
|August 20, 2005
Summary
Encapsulating peritoneal sclerosis (EPS) is a rare complication of chronic peritoneal dialysis (CPD) in children. This study found an incidence of 1.9% in paediatric patients, highlighting the need for radiological evaluation in cases of ultrafiltration failure.
Area of Science:
- Nephrology
- Pediatric Nephrology
- Gastroenterology
Background:
- Encapsulating peritoneal sclerosis (EPS) is a severe complication of chronic peritoneal dialysis (CPD).
- Limited data exists on EPS in pediatric CPD patients, with most reports from Japan.
- This study aimed to determine the incidence and characteristics of EPS in a pediatric CPD cohort.
Observation:
- Two out of 104 pediatric patients (1.9%) were diagnosed with EPS.
- Patients had dialysis durations of 45 and 53 months with 6 and 8 peritonitis episodes.
- EPS symptoms appeared 7-14 days post-catheter removal, leading to CPD cessation and transition to hemodialysis due to persistent peritonitis.
Findings:
- One patient managed surgically experienced short-term recovery before mortality.
- Another patient treated with prednisolone showed sustained improvement at 16 months.
- EPS is a rare but significant complication of pediatric CPD.
Implications:
- Pediatric CPD patients presenting with ultrafiltration failure should undergo radiological assessment for EPS.
- Tailored management strategies are crucial for individual pediatric EPS cases.
- Further research is needed to understand and prevent EPS in pediatric populations.