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Related Experiment Videos

Relation between migraine and stroke.

Marie-Germaine Bousser1, K Michael A Welch

  • 1Hôpital Lariboisière, Service de Neurologie, Paris, France. mg.bousser@lrb.aphp.fr

The Lancet. Neurology
|August 20, 2005
PubMed
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Migraine with aura (MA) and ischaemic stroke have a complex, bidirectional relationship. While MA increases stroke risk, especially in young women, stroke can also trigger MA, indicating shared vascular causes.

Area of Science:

  • Neurology
  • Vascular Neurology
  • Epidemiology

Background:

  • A known complex bidirectional relationship exists between migraine, particularly migraine with aura (MA), and ischaemic stroke.
  • Cerebral infarction can manifest during MA, establishing MA as a significant risk factor for ischaemic stroke, especially in younger women.
  • Conversely, cerebral ischaemia has the potential to induce MA, highlighting a complex interplay.

Purpose of the Study:

  • To elucidate the intricate bidirectional relationship between migraine with aura and ischaemic stroke.
  • To explore the potential shared underlying vascular pathologies contributing to both conditions.
  • To contextualize the risk associated with MA in the broader spectrum of primary headache disorders.

Main Methods:

  • Review of existing literature on migraine with aura and ischaemic stroke.

Related Experiment Videos

  • Analysis of epidemiological data linking MA and stroke incidence.
  • Examination of pathophysiological mechanisms underlying both neurological events.

    • Main Results:

    • Migraine with aura is a confirmed risk factor for ischaemic stroke, particularly in young women.
    • A reciprocal relationship is observed, where cerebral ischaemia can precipitate MA.
    • Shared vascular risk factors likely underlie the association between MA and ischaemic stroke.

    Conclusions:

    • The relationship between MA and ischaemic stroke is complex and bidirectional.
    • Underlying vascular disorders are implicated in both MA and ischaemic stroke.
    • Despite the association with stroke, migraine as a primary headache disorder is generally considered benign.