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Related Experiment Videos

Neonate capillary blood gas reference values.

Jocelyne Cousineau1, Suzanne Anctil, Ana Carceller

  • 1Department of Clinical Biochemistry, CHU Ste-Justine, Université de Montréal, Québec, Canada.

Clinical Biochemistry
|August 20, 2005
PubMed
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This study establishes current capillary blood reference values for blood gases, lactate, ionized calcium, and glucose in healthy term neonates. These updated values are crucial due to technological advancements in blood gas analysis.

Area of Science:

  • Neonatal Medicine
  • Clinical Chemistry
  • Biomedical Engineering

Background:

  • Published reference values for neonatal blood gases, lactate, ionized calcium (iCa), and glucose may be outdated due to technological evolution over two decades.
  • Instrument-dependency of biological data necessitates updated reference ranges.
  • Current values are needed to accurately assess the physiological status of neonates.

Purpose of the Study:

  • To determine current capillary blood reference values for blood gases (pH, pO2, pCO2), lactate, ionized calcium (iCa), and glucose.
  • To provide updated data for healthy term neonates at 48 +/- 12 hours of life.
  • To establish a contemporary baseline for neonatal clinical chemistry.

Main Methods:

  • Utilized extra blood samples from heel-pricks performed for the Quebec genetic screening program.

Related Experiment Videos

  • Included 126 term neonates (gestational age 39.6 +/- 1.2 weeks).
  • Simultaneously measured pH, pO2, pCO2, lactate, iCa, and glucose using selective electrodes on an ABL 735 blood gas analyzer.

    • Main Results:

    • All measured variables demonstrated a Gaussian distribution.
    • No significant gender effect was observed, allowing for pooled data analysis.
    • Established current reference ranges for key blood analytes in term neonates.

    Conclusions:

    • The study provides current, reliable reference values for capillary blood gases, lactate, ionized calcium, and glucose in healthy term neonates.
    • These updated values are essential for accurate interpretation of neonatal laboratory results.
    • The findings support the use of contemporary reference ranges in neonatal care and research.