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Updated: Aug 16, 2026

Long-Term Continuous Measurement of Renal Blood Flow in Conscious Rats
Published on: February 8, 2022
[Experimental study of the characteristics of renal blood flow with contrast ultrasound]
Jin-guo Xie1, Ping Zeng, Wen-xing Xiao
1Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. xajngo@fimmu.com
Objective:
To study the characteristics of renal blood flow with contrast ultrasound.
Methods:
The examination of the renal ultrasonography was performed in 10 dogs after intravenous injection of Quanfuxian (a contrast agent consisting of C3F8 microbubbles).
Results:
Contrast visualization appeared in the renal cortex and then in the outer to inner medulla at the baseline level after administration of the contrast agent. Notable differences in the values of microvascular volume (A, which was 120.3 in the corted vs 110.8 in the medulla, P>0.05), microcirculatory flow velocity (beta, which was 1.39 in the corted vs 0.54 in the medulla, P<0.05), and microcirculatory flow rate (A x beta, 167.4 in the corted vs 59.5 in the medulla, P<0.05) were found between the corted and the medulla, with also marked difference between the the corted-to-the medulla ratios of beta and A (0.612 vs 0.078, P<0.05).
Conclusion:
Contrast ultrasound of the kidney provides a useful means of renal circulatory flow study.
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