[Daily dynamics of iron excretion with murine in experimental hepatosis]

Experimental hepatosis induced by intragastric administration of CCl4 was revealed to be accompanied by changes in temporal organization of lipid peroxidation, sideremia and iron excretion with urine. Even at early stages of organ lesions, the activation of free-radical lipid oxidation and rearrangement of sideruria circadian rhythm were found to result in a substantial and stable increase in mesor of the trace element excretion with urine in spite of a statistically significant decrease in water release.