Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Progress in type III secretion system].

Li Wang1, Yu-Ming Wang, Jun-Jie Yue

  • 1State Key Laboratory of Medical Microbiology and Biosafety, Institute of Biotechnology, Academy of Military Sciences, Beijing 100071, China. wangl@bioinf.bmi.ac.cn

Wei Sheng Wu Xue Bao = Acta Microbiologica Sinica
|August 23, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Vaccine with Multiple Receptor-Binding Domain Subunit Mutations Induces Broad-Spectrum Immune Response against SARS-CoV-2 Variants of Concern.

Vaccines·2022
Same author

[Distribution of Micro-plastics in the Soil Covered by Different Vegetation in Yellow River Delta Wetland].

Huan jing ke xue= Huanjing kexue·2020
Same author

Genome-Wide Identification and Analysis of Enhancer-Regulated microRNAs Across 31 Human Cancers.

Frontiers in genetics·2020
Same author

Characterization of PM<sub>2.5</sub>-bound phthalic acid esters (PAEs) at regional background site in northern China: Long-range transport and risk assessment.

The Science of the total environment·2019
Same author

Analysis on the interaction domain of VirG and apyrase by pull-down assay.

Molecules (Basel, Switzerland)·2014
Same author

Design, synthesis and evaluation of novel 4-dimethylamine flavonoid derivatives as potential multi-functional anti-Alzheimer agents.

Bioorganic & medicinal chemistry·2013
Same journal

[Physiological function of membrane protein RHOGL009301 involved in transport of benzoate in Rhodococcus sp. R04].

Wei sheng wu xue bao = Acta microbiologica Sinica·2018
Same journal

[Distribution, structure and sequence alignment, and metagenomics analysis of two nitrite reductases with NO forming].

Wei sheng wu xue bao = Acta microbiologica Sinica·2018
Same journal

[Diversity of microbial community structure in the spermosphere of saline-alkali soil in shandong area].

Wei sheng wu xue bao = Acta microbiologica Sinica·2018
Same journal

[Two sample pooling strategies revealed different root-associated fungal diversity of Rhododendron species].

Wei sheng wu xue bao = Acta microbiologica Sinica·2018
Same journal

[Phylogenetic and genetic heterogeneity of 23 Acidithiobacillus strains isolated from different geographical locations].

Wei sheng wu xue bao = Acta microbiologica Sinica·2018
Same journal

[Effects of glucose on photosynthesis and growth of Chloralla sp. HN08 cells].

Wei sheng wu xue bao = Acta microbiologica Sinica·2018
See all related articles

Type III secretion system (TTSS) chaperone proteins are crucial for injecting bacterial toxins. This review details their classification, function, and interactions, clarifying their enigmatic roles in diseases like plague and typhoid.

Area of Science:

  • Microbiology
  • Molecular Biology
  • Bacteriology

Context:

  • Gram-negative bacteria utilize the Type III Secretion System (TTSS) to deliver effector proteins into host cells.
  • The TTSS is a critical virulence factor responsible for diseases such as plague, typhoid fever, and various diarrheal illnesses.
  • Chaperone proteins, a key component of the TTSS, are essential for the efficient secretion of these effector proteins.

Purpose:

  • To review the current understanding of TTSS chaperone proteins.
  • To elucidate the classification and diverse functions of these essential proteins.
  • To describe the molecular interactions between chaperones and their substrate proteins.

Summary:

  • This review consolidates recent advancements in the study of TTSS chaperone proteins.

Related Experiment Videos

  • It covers their classification based on structural and functional characteristics.
  • The review highlights the known functions and substrate interaction specificities of these chaperones, shedding light on their previously enigmatic roles.

    • Impact:

    • Provides a comprehensive overview of TTSS chaperone proteins for researchers.
    • Facilitates a deeper understanding of bacterial pathogenesis mechanisms.
    • Offers insights into potential targets for novel antimicrobial strategies against TTSS-dependent pathogens.