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Cutaneous lymphoid hyperplasia and marginal zone B-cell lymphoma following vaccination
Steve A May1, George Netto, Rana Domiati-Saad
1Department of Pathology, Baylor University Medical Center, Dallas, Texas, USA.
Abstract:
Atypical lymphoid infiltrations arose within the influenza inoculation sites of two adult female patients. One patient developed a low-grade cutaneous marginal zone B-cell lymphoma (MZL) that was responsive to local excision and radiation therapy despite spread to a distant cutaneous site. The second patient's clinical course was characterized by a locally aggressive, histologically reactive inflammatory reaction responsive only to radiation therapy after multiple failed attempts at surgical resection.
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