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Particular clinical features of psoriasis in infants and chidren
Insights
Childhood psoriasis, affecting 15% of patients before age 10, presents uniquely. This study explores uncommon childhood psoriasis forms, including generalized pustular infantile psoriasis and infantile arthropathic psoriasis.
Area of Science:
- Pediatric Dermatology
- Immunodermatology
Background:
- Psoriasis onset before age 10 affects 15% of patients.
- Childhood psoriasis often exhibits peculiar clinical patterns.
- Diagnosis can be challenging with early-onset or specific location psoriasis.
Purpose of the Study:
- To investigate the less common clinical presentations of childhood psoriasis.
- To highlight diagnostic challenges in early-onset psoriasis.
- To focus on specific rare forms like infantile generalized pustular psoriasis and arthropathic psoriasis.
Main Methods:
- Review of clinical cases of childhood psoriasis.
- Analysis of distinct and uncommon psoriasis phenotypes in children.
- Comparative study of typical and atypical presentations.
Main Results:
- Psoriasis guttata and nummular psoriasis are common initial childhood forms.
- Difficulties in diagnosing psoriasis on scalp, palms, soles, digits, and nails.
- Napkin psoriasis onset at 3 months; Leiner's disease can evolve into chronic psoriasis.
- Focus on generalized pustular infantile form, congenital/acquired psoriatic erythroderma, and infantile arthropathic psoriasis.
Conclusions:
- Childhood psoriasis presents diverse and sometimes challenging clinical features.
- Understanding rare forms is crucial for accurate diagnosis and management.
- Further research into infantile pustular and arthropathic psoriasis is warranted.
Abstract:
The onset of psoriasis is observed before the age of 10 years in 15% of all patients. The clinical pattern often takes on a peculiar form. Psoriasis guttata--or less frequently nummular psoriasis--is the initial phase during childhood. It is very difficult to establish a diagnosis on the basis of incipient features when childhood psoriasis is located on the head, palms, soles, or on the fingers, toes and nails. Intertriginous or flexural psoriasis, psoriasis spinulosa and oral psoriasis is also described. The onset of napkin psoriasis starts at the age of 3 months. Occasionally, Leiner's disease may develop into a typical, chronic psoriasis. We have concentrated our studies on the less common features of childhood psoriasis: the generalized pustular infantile form, congenital psoriatic erythroderma, acquired psoriatic erythroderma, and infantile arthropathic psoriasis.