Aptamer biosensor for label-free impedance spectroscopy detection of proteins based on recognition-induced switching of the surface charge
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Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor
Published on: February 16, 2018
Marcela C Rodriguez1, Abdel-Nasser Kawde, Joseph Wang
1Department of Chemical and Material Engineering, Biodesign Institute, Arizona State University, Tempe, AZ 85287-5801, USA.
Abstract:
The recognition of proteins by aptamer-modified electrode transducers reverses the surface charge and leads to a novel label-free impedance spectroscopy bioelectronic detection protocol based on a decrease in the electron transfer resistance.

