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Updated: Aug 16, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
[Multiprofessional care and mental health in pregnant women]
Vanda Mafra Falcone1, Custódia Virginia de Nóbrega Mäder, Christianne Freitas Lima Nascimento
1Centro de Promoção e Atenção à Saúde, Instituto de Ensino e Pesquisa, Hospital Albert Einstein, São Paulo, SP, Brasil. penc@einstein.br
Objective:
To identify non-psychotic affective disorders in pregnant women, to intervene by means of psychoprophylactic groups, and to evaluate possible alterations following intervention.
Methods:
One-hundred and three pregnant women (71 adults and 32 adolescents) were seen at a community program in the Paraisópolis neighborhood in the city of Sao Paulo, southeastern Brazil. We used the following instruments: Self Reporting Questionnaire and Beck Depression Inventory. Ten weekly two-hour meetings were held, addressing the link between mother and fetus and subjects related to mother and child, and answering mother's doubts. We used the chi-squared test (chi2) to compare mental health before and after the intervention, with a significance level of p<0.05.
Results:
Affective disorders were found in 45 pregnant women (43.7%) before the intervention and in 23 (22.3%) after the intervention. The impact of the intervention on affective disorders was statistically significant (p=0.001). Twenty-one women (20.4%) showed depression before the intervention, and 13 (12.6%) after the intervention, a non-significant difference (p=0.133).
Conclusions:
Multiprofessional care can prevent, detect, and treat affective disorders during pregnancy in both adults and adolescents.
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