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Elective hepatic resection in the elderly.

G Mentha1, O Huber, J Robert

  • 1Department of Digestive Surgery, University Hospital, Geneva, Switzerland.

The British Journal of Surgery
|June 1, 1992
PubMed
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Elective liver resection is safe for elderly patients without cirrhosis. Minimizing intraoperative blood loss is key to reducing mortality and hospital stay in this age group.

Area of Science:

  • Hepatobiliary Surgery
  • Geriatric Surgery
  • Surgical Oncology

Background:

  • Elective liver resection is a complex procedure.
  • The safety and efficacy in elderly patients (over 64 years) require specific evaluation.
  • Pre-existing conditions like cirrhosis can impact outcomes.

Purpose of the Study:

  • To assess the safety and validity of elective liver resection in patients aged 64 years and older.
  • To compare outcomes in elderly patients with younger cohorts.
  • To identify factors influencing mortality and postoperative stay in this demographic.

Main Methods:

  • Retrospective review of 293 elective liver resections performed between 1967 and 1990.
  • Analysis of a subgroup of 52 patients aged over 64 years.

Related Experiment Videos

  • Comparison of mortality rates and hospital stay durations between age groups and resection types.

    • Main Results:

    • The elderly subgroup (52 patients) had a 6% mortality rate (2 deaths from hepatic failure, 1 from cardiac failure).
    • Mortality and hospital stay were not significantly different compared to younger patients without cirrhosis (P=0.39).
    • Intraoperative blood loss was the sole significant predictor of mortality (P=0.008) and hospital stay (P=0.04).

    Conclusions:

    • Elective liver resection can be safely performed in elderly patients without cirrhosis.
    • Careful management to minimize intraoperative blood loss is crucial for optimal outcomes.
    • Age alone should not be a contraindication for liver resection in the absence of cirrhosis.