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Updated: Aug 16, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Toward solving the sedation-assessment conundrum: bi-spectral index monitoring and sedation interruption
Daiwai M Olson1, Carmelo Graffagnino, Kenneth King
1The University of North Carolina at Chapel Hill, School of Nursing, Chapel Hill, NC 27599-7460, USA. dmOlsen@email.unc.edu
Abstract:
The sedation-assessment conundrum is defined by two diametrically opposed goals: to maintain an appropriate level of sedation, and to obtain a comprehensive neurologic examination that most accurately reflects the patient's neurologic status. A case presentation leads to a discussion of over-sedation and under-sedation issues that impact the care of critically ill patients. This information is useful in understanding the many methods of assessing sedation and interpreting individualized patient responses to sedation. The use of bi-spectral index monitoring and periods of sedation interruption are discussed within the context of addressing the sedation-assessment conundrum.
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