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Tolerance of a milk-based formula by infants
1Wyeth Limited, North York, Ontario, Canada.
Insights
A standard milk-based infant formula supports healthy growth in infants under 12 months. Most infants tolerated the formula well, with reported improvements in digestive symptoms and spitting up.
Area of Science:
- Pediatrics
- Infant Nutrition
- Gastroenterology
Background:
- Infant formula is a primary nutrition source for many infants.
- Assessing formula tolerance and impact on infant development is crucial.
- Standard milk-based formulas are widely used globally.
Purpose of the Study:
- To evaluate the tolerance and efficacy of a standard, low-iron, milk-based infant formula.
- To assess the impact of the formula on infant growth parameters.
- To monitor common infant symptoms associated with feeding.
Main Methods:
- A cohort of 781 healthy infants under 12 months received the formula.
- Infant weight and length were monitored throughout the study period.
- Parent-reported symptoms of intolerance were collected before and during the study.
Main Results:
- Infants demonstrated normal weight and length increases, indicating adequate nutrition.
- The formula was well tolerated by the majority of the study population.
- Significant reductions in colic, constipation, diarrhea, loose stools, skin rashes, and spitting up were observed.
Conclusions:
- Standard milk-based infant formula is generally well-tolerated by healthy infants.
- The formula supports healthy physical development.
- The studied formula may alleviate common infant digestive discomforts.
Abstract:
A standard, low-iron, milk-based formula was fed to 781 healthy infants younger than 12 months of age. The infants showed normal increases in weight and length during the study. The formula was well tolerated by most of the infants. The most frequently reported symptoms of intolerance before and during the study were loose stools (in 78%) and spitting up (in 79%). A significant decrease from before to after the study was reported in the symptoms of colic, constipation, diarrhea, loose stools, skin rashes, and spitting up. It is concluded that a standard milk-based formula is well tolerated by most healthy infants.