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Published on: September 22, 2023
[Cardiovascular imaging in preventive medicine]
1European Prevention Center, München. uwe.nixdorff@t-online.de
Insights
Atherosclerosis, a silent killer, requires individualized risk assessment beyond traditional factors. Advanced imaging provides crucial preclinical data for effective prevention strategies.
Area of Science:
- Cardiovascular Medicine
- Medical Imaging
- Preventive Cardiology
Context:
- Atherosclerosis is a leading cause of death in Europeans, often progressing silently.
- Current treatments focus on risk reduction but often fall short in capturing individual disease progression.
- Traditional risk factors like hypertension and lipid disorders lack precision in predicting individual atherosclerotic trajectories.
Purpose:
- To highlight the limitations of traditional risk factor assessment in atherosclerosis.
- To emphasize the value of advanced imaging in evaluating preclinical atherosclerotic disease.
- To advocate for individualized risk stratification using imaging-derived surrogate markers.
Summary:
- Atherosclerosis is a major cause of mortality, necessitating improved preventive strategies.
- Advanced imaging modalities offer superior insights into the atherosclerotic process compared to traditional risk factors.
- These imaging techniques provide validated surrogate parameters for assessing preclinical disease and guiding preventive interventions.
Impact:
- Individualized risk stratification using imaging can enhance primary and secondary prevention of atherosclerosis.
- This approach promises more cost-effective and personalized cardiovascular risk management.
- Improved preclinical detection through imaging may reduce atherosclerosis-related mortality and morbidity.
Abstract:
Atherosclerosis is a systemic, over a long period silent, but at least in many cases severe illness with fatal events which in most Europeans represent the reason of death. The primary reduction of causative factors is very efficient, but, however, is not readily enough established within dominant curative treatment. In contrary, a cost effective risk modification is possible, especially by individualized risk stratification. The assessment of traditional risk factors (like lipid disorders, arterial hypertension) can not display the individual progression within the pathophysiologic continuum. Imaging modalities that examine morphology and function are able to assess preclinical data that represent validated surrogate parameters of the atherosclerotic process and in addition to traditional risk factors predictive informations. Predominantly, they allow the concept of primary and secondary preventive strategies.
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