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Updated: Aug 16, 2026
Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
Published on: February 27, 2026
[T2N1M0 non-small cell lung cancer: surgery and prognostic factors]
J Padilla1, V Calvo, J C Peñalver
1Servicio de Cirugía Torácica, Hospital Universitario La Fe, Valencia, España. jpadilla@comv.es
Objective:
To determine the prognostic factors for the survival in a group of patients operated on for a non-small cell lung cancer classified as T2N1M0.
Patients And Methods:
Two hundred sixteen patients treated exclusively with surgery were studied. Kaplan-Meier survival and Cox multivariable regression analyses were used.
Results:
The overall survival rate was 39.8% at 5 years and 29.9% at 10 years. Sex, age, presence or absence of symptoms, type of resection, number, and location of affected lymph nodes had no effect on survival. Tumor size (P=.04) and histologic type (P=.03) did significantly affect prognosis. Both variables entered into the Cox multivariable regression model.
Conclusions:
Patients operated on for non-small cell lung cancer classified as T2N1M0 have an overall probability of 5-year survival of approximately 40%. However, the prognosis for this group of patients is heterogeneous: in our study it was affected by the histologic type (45.5% for squamous cell and 25% for non-squamous cell cancers) and tumor size (53% for tumors with a diameter of