Related Experiment Video
Updated: Aug 16, 2026

Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis
Published on: December 30, 2025
Hyperthyroidism and cerebral venous thrombosis
S Mouton1, N Nighoghossian, M Berruyer
1Cerebrovascular Disease Center, Lyon, France.
Abstract:
The demonstration of an underlying prothrombotic condition in cerebral venous thrombosis (CVT) may have important practical consequences in terms of prevention. Thyrotoxicosis through a hypercoagulable state may be a predisposing factor for CVT. The authors present the cases of 4 patients who developed CVT and hyperthyroidism. At the acute stage, hyperthyroidism was associated with an increase in factor VIII (FVIII). At follow-up, FVIII level remained increased in 2 patients. Hyperthyroidism may have an impact on FVIII level. Accordingly in patients with hyperthyroidism and neurological symptoms, the diagnosis of CVT should be considered and an exhaustive coagulation screening may be appropriate.
Related Concept Videos
Hyperthyroidism II: Pathophysiology
Venous Thrombosis I: Introduction
Graves' Disease I: Introduction
Increased Intracranial Pressure l: Introduction
Cerebral Edema ll: Pathophysiology
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies