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Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
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Published on: October 12, 2012

The paradox of heparin-induced thrombocytopenia: future anticoagulation

Lisa M Taylor1, Kelly M Smith

  • 1University of Kentucky Chandler Medical Center, Lexington, Ky, USA.

Orthopedics
|August 27, 2005
PubMed

Heparin and low molecular weight heparin agents are frequently administered to postoperative orthopedic patients. In patients with a history of heparin-induced thrombocytopenia, alternative anticoagulant agents to heparin for prophylaxis and treatment must be considered. Unfortunately, the data is limited in this patient population. Upon transitioning from heparin-induced thrombocytopenia treatment with direct thrombin inhibitors, argatroban, or lepirudin, careful consideration must be taken to avoid further thrombotic complications.

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