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Updated: Aug 17, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[The question of oral sedation using midazolam in outpatient dental surgery]
U W Wahlmann1, U Dietrich, W Fischer
1Poliklinik für Zahnärztliche Chirurgie der Universität Mainz.
Abstract:
The aim of the present study was to evaluate the effect of one tablet of midazolam (Dormicum 7.5 mg) used as a premedicant for minor oral surgery and to assess the potential risk of hypoventilation. In all of the patients no significant drop in arterial oxygen saturation could be observed, but on the other hand, no real anxiolytic or amnestic effects either. With the little therapeutic use observed with the given premedication, a more widespread application of the substance in this dosage cannot be recommended, particularly when taking into account the possibility of complications and the loss of the patients's fitness to drive for the next twelve hours.
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