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Updated: Aug 16, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Sclerosing panniculitis is associated with pulmonary hypertension in systemic sclerosis
1Department of Dermatology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-8655, Japan.
Background:
There have been no reports of patients with sclerosing panniculitis and systemic sclerosis (SSc).
Objectives:
To evaluate the incidence of sclerosing panniculitis in patients with SSc, and to investigate the clinical features of such cases.
Methods:
In total, 128 patients with SSc treated at our clinic were investigated retrospectively.
Results:
SSc patients with sclerosing panniculitis had pulmonary hypertension (PH), especially isolated PH, at a significantly higher incidence than those without. Among the SSc patients with PH, those with sclerosing panniculitis had pulmonary infarctions at a higher incidence than those without.
Conclusions:
Our results suggest that thrombosis caused by venous hypertension of the leg may be the main cause of PH in patients with SSc and sclerosing panniculitis. Sclerosing panniculitis may be a useful marker of PH in patients with SSc.
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