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HIV neuromuscular disease and mitochondrial function

Lydia Estanislao1, Diane Thomas, David Simpson

  • 1Neuro-AIDS Research Program, Department of Neurology, Box 1052, Mount Sinai Medical Center, New York, NY 10029, USA. lydia.estanislao@mssm.edu

Mitochondrion
|August 27, 2005
PubMed

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Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
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