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A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
Published on: August 8, 2014
[Localized aggressive periodontitis: a possible site-specific rather than tooth-specific disease?]
1Dept. of Periodontics, The Hebrew University-Hadassah School of Dental Medicine, Jerusalem.
Summary
Localized aggressive periodontitis may target specific sites, not just teeth. This case study during orthodontic treatment challenges the traditional tooth-specific diagnosis for aggressive periodontitis.
Area of Science:
- Periodontology
- Orthodontics
- Oral Medicine
Background:
- Localized aggressive periodontitis diagnosis traditionally requires first molar attachment loss.
- This diagnostic criterion has remained unquestioned until now.
- Aggressive periodontitis can occur during orthodontic treatment.
Observation:
- A rare case of aggressive periodontitis developed during orthodontic therapy.
- This involved extraction of a first molar and repositioning of a second molar.
- Periodontal disease manifested at the original first molar site and the site now occupied by the moved second molar.
Findings:
- The study presents evidence suggesting aggressive periodontitis can be site-specific rather than tooth-specific.
- Bacterial-induced aggressive periodontitis developed in a localized manner during orthodontic treatment.
- The findings challenge the established tooth-specific diagnostic criteria.
Implications:
- This case suggests a re-evaluation of the diagnostic criteria for localized aggressive periodontitis is warranted.
- Understanding site-specificity could lead to more targeted periodontal treatments.
- Further research is needed to explore the site-specific hypothesis in aggressive periodontitis.
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