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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Aortic homograft: a suitable substitute for aortic valve replacement.
Sachin Talwar1, Raghunath Mohapatra, Anita Saxena
1Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi, India.
The Annals of Thoracic Surgery
|August 27, 2005
Summary
Aortic valve replacement using aortic homografts shows acceptable mortality and good midterm outcomes. Both surgical techniques, scalloped subcoronary and root replacement, yielded similar results for homograft function and reoperation rates.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Cardiac Valve Surgery
Background:
- Aortic valve disease necessitates surgical intervention, with aortic homografts being a viable option.
- Assessing the long-term efficacy and safety of aortic homograft use is crucial for patient management.
Purpose of the Study:
- To evaluate the outcomes of aortic valve replacement (AVR) utilizing aortic homografts.
- To compare the effectiveness of different surgical techniques for AVR with aortic homografts.
Main Methods:
- A retrospective analysis of 154 patients undergoing AVR with aortic homografts between January 1994 and September 2003.
- Procedures included scalloped subcoronary (n=110), root replacement (n=38), and valved homograft conduit (n=6) techniques.
- Associated cardiac procedures were also performed, including mitral valve repair and coronary artery bypass grafting.
Main Results:
- Early mortality was 7.8%, with a mean follow-up of 62 months.
- 87.3% of survivors had trivial to mild aortic regurgitation.
- Actuarial survival was 92.2%, and reoperation-free survival was 95.8%. Freedom from significant aortic stenosis or regurgitation was 86.1%.
Conclusions:
- Aortic valve replacement with aortic homografts offers acceptable early and late mortality.
- Satisfactory midterm results were observed, with no significant difference in homograft dysfunction or reoperation rates between surgical techniques.
