Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A multi-institutional experience with the CryoMaze procedure.

James S Gammie1, John C Laschinger, James M Brown

  • 1Division of Cardiac Surgery, University of Maryland Medical Center, Baltimore, MD 21201, USA. jgammie@smail.umaryland.edu

The Annals of Thoracic Surgery
|August 27, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Noninvasive Monitoring of Complement Using the Bioluminescent Modified Ham Assay in the Second Porcine-to-Human Live Heart Transplant.

Xenotransplantation·2026
Same author

Case Report: When inotropy backfires-dobutamine-associated eosinophilic myocarditis.

Frontiers in cardiovascular medicine·2026
Same author

Device-Induced Blood Damage in Pump-Assisted Circulation: A Comparative Study of HeartMate III and BrioVAD Pumps.

Artificial organs·2026
Same author

Perspectives on the 2026 ISHLT Consensus Statement on Clinical Cardiac Xenotransplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

Platelet Adhesion and Aggregation Dynamics over Collagen- and VWF-coated Surfaces: Insights from Dissipative Particle Dynamics Simulations and Microfluidic Experiments.

Bulletin of mathematical biology·2026
Same author

The 2026 International Society for Heart and Lung Transplantation Consensus Statement on clinical cardiac xenotransplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026

The CryoMaze operation effectively treats atrial fibrillation (AF), achieving normal sinus rhythm in 95% of patients. This surgical technique offers comparable success rates to the traditional Cox-Maze III procedure.

Area of Science:

  • Cardiovascular Surgery
  • Electrophysiology
  • Minimally Invasive Techniques

Background:

  • The Cox Maze III operation is the established surgical standard for treating atrial fibrillation (AF).
  • This study investigates the CryoMaze operation, utilizing a flexible argon-powered cryoprobe to create the Cox-Maze III lesion set.
  • Atrial fibrillation affects a significant patient population, necessitating effective surgical interventions.

Purpose of the Study:

  • To evaluate the efficacy and safety of the CryoMaze operation for treating atrial fibrillation.
  • To compare the outcomes of the CryoMaze operation with the established Cox-Maze III procedure.
  • To assess the medium-term success rate of achieving normal sinus rhythm after CryoMaze surgery.

Main Methods:

  • Thirty-eight patients underwent the CryoMaze operation between July 2002 and December 2003.

Related Experiment Videos

  • Procedures included isolated CryoMaze in two patients and combined with other cardiac surgeries in 36 patients.
  • All patients received electrocardiographic follow-up to monitor rhythm status.
  • Main Results:

    • No complications were associated with cryoenergy use.
    • One hospital death (2.6%) occurred; no late deaths were reported.
    • At a mean 12-month follow-up, 95% (35 of 37) of patients were in normal sinus rhythm; no thromboembolic events occurred.

    Conclusions:

    • The CryoMaze operation provides a reliable cure for atrial fibrillation with medium-term follow-up.
    • Success rates for the CryoMaze operation are comparable to the classic Cox-Maze III procedure.
    • CryoMaze offers a safe and effective alternative for surgical AF treatment.