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Pregnancy outcome after exposure to injectable ribavirin during embryogenesis

Massoud Rezvani1, Gideon Koren

  • 1The Hospital for Sick Children, Division of Clinical Pharmacology, The Motherisk Program, 555 University Avenue, Toronto, Ont., Canada M5G 1X8.

Reproductive Toxicology (Elmsford, N.Y.)
|August 27, 2005
PubMed

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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...