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Updated: Aug 16, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Problems with attempted chorioretinal venous anastomosis by laser for nonischemic CRVO and BRVO
Tayfun Bavbek1, Ozlem Yenice, Okan Toygar
1Department of Ophthalmology, Marmara University Medical School, Istanbul, Turkey.
Purpose:
To report the complications and long-term results of laser-induced chorioretinal venous anastomosis in vein occlusions.
Patients And Methods:
Eight consecutive eyes, 3 with central retinal vein (CRVO) and 5 with branch retinal vein occlusion (BRVO), were observed for up to 5 years after attempted laser-induced chorioretinal venous anastomosis.
Results:
Successful chorioretinal venous anastomoses were created in 2 (25%) eyes. Patients had severe complications, including vitreous hemorrhage, choroidal neovascular membrane, choriovitreal neovascularization, rubeosis iridis and neovascular glaucoma.
Conclusion:
The utilization of a chorioretinal venous anastomosis by laser with proposed laser settings as a therapeutic modality should be further analyzed, and a careful long-term follow-up must be done to avoid vision-threatening complications.

