Related Experiment Video
Updated: Aug 16, 2026
Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
Published on: August 9, 2012
Consistency of urodynamic parameters in children with detrusor instability: how many times should the bladder be
Selami Sözübir1, Ahmet Celik, Nilüfer Emir
1Department of Pediatric Surgery, Division of Pediatric Urology, Ege University Faculty of Medicine, Izmir, Turkey. selamisz@superonline.com
Insights
Performing two bladder fillings during urodynamic studies is sufficient for diagnosing detrusor instability in children. This approach ensures reliable assessment while minimizing patient distress.
Area of Science:
- Pediatric Urology
- Urodynamics
Background:
- Standard urodynamic studies recommend at least two bladder fillings.
- This procedure can be time-consuming and distressing for patients and healthcare professionals.
Purpose of the Study:
- To evaluate the impact of the number of bladder fillings on urodynamic parameters.
- To compare findings in children with normal urodynamic results versus those with detrusor instability.
Main Methods:
- Retrospective review of urodynamic data from 112 children (70 with detrusor instability, 42 normal).
- Analysis of three consecutive bladder fillings, comparing mean bladder capacity ratio, maximum filling pressure, and number of contractions.
Main Results:
- In children with normal urodynamics, bladder capacity remained consistent, but maximum filling pressures decreased with subsequent fillings.
- Children with detrusor instability showed a higher number of contractions during the first filling, with significant differences in mean bladder capacity and decreased maximum filling pressures across fillings.
Conclusions:
- At least two bladder fillings are recommended for reliable urodynamic assessment in suspected detrusor instability.
- Two normal fillings, characterized by absence of contractions, normal capacity, and normal maximum filling pressure, strongly suggest a normal third filling.
Introduction:
It is recommended that the bladder be filled at least twice to perform a standard urodynamic study. However, the procedure is time-consuming and distressing for both the patient and the professional. The impact of the number of fillings on urodynamic parameters in children with normal urodynamic results and those with detrusor instability is presented in this study.
Patients And Methods:
Urodynamic data from 70 children with detrusor instability and 42 with normal urodynamic parameters who had undergone 3 consecutive fillings in a single session during a 2-year period were reviewed retrospectively. The variable parameters that were compared between the 2 groups were the mean bladder capacity ratio, maximum filling pressure and the number of contractions during the filling phase.
Results:
In the normal group, no difference was found in bladder capacities between the 3 fillings, but there was a significant decrease in the maximum bladder filling pressures in the subsequent fillings. In children with detrusor instability, the number of contractions in the 1st filling was significantly higher than those in the subsequent fillings. Also in this group, a significant difference in the mean bladder capacities between fillings was noted as well as a decrease in the maximum bladder filling pressures in contrast to normal bladders.
Conclusion:
In patients with suspected detrusor instability the bladder should be filled at least twice for a reliable urodynamic assessment. Two normal fillings without contractions, with normal capacity and normal maximum bladder filling pressure are highly suggestive of a normal 3rd filling.
Related Concept Videos
01:19Urodynamic Studies: Uroflowmetry
01:26The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating urine...
01:23Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
01:19Anatomy of the Genitourinary System II: Bladder and Urethra
01:22Imaging Studies VI: Voiding Cystourethrography and Cystography
01:24Imaging Studies II: Ultrasonography