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Updated: Aug 15, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Malignant melanoma with metastasis into the capitate
Xavier Tomas1, Carles Conill, Andreu Combalia
1Radiology Department (CDIC), Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Facultat de Medicina, Universitat de Barcelona, Villarroel 170, Barcelona 08036, Spain. 22812xtb@comb.es
Abstract:
Metastases to the hand and wrist are rare, with fewer than 200 cases reported in the literature. Phalanges are more commonly involved than metacarpal and wrist. The lung, breast and kidneys are the more common sites of primary lesions than metastasize in the hand. We present an exceptional case of melanoma that metastasized to the capitate. Melanoma can give bone metastases, but we are not aware of reports of this tumour metastatising to the carpal bones. In our knowledge, we have only found a report of metastases in the capitate, a clear-cell sarcoma of the right foot, a tumour close to melanoma with some cytogenetic differences. Hand metastases in a patient who is suffered melanoma should be ruled out if a lytic aggressive lesion appears on x-ray film or positive technetium bone scan is demonstrated.
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