Related Experiment Videos
[Improvement of hemorheology with ginkgo biloba extract. Decreasing a cardiovascular risk factor]
Insights
This study found that ginkgo biloba extract (EGb 761) improved fibrinogen levels and hemorrheological properties in outpatients with cardiovascular risk factors. Long-term treatment positively influenced these key cardiovascular indicators.
Area of Science:
- Cardiovascular Medicine
- Pharmacology
- Hemodynamics
Background:
- Elevated fibrinogen levels and plasma viscosity are significant cardiovascular risk factors.
- Common underlying conditions include coronary heart disease, hypertension, hypercholesterolemia, and diabetes mellitus.
Purpose of the Study:
- To investigate the effect of ginkgo biloba extract (EGb 761) on fibrinogen levels and hemorrheological properties.
- To assess the long-term influence of EGb 761 on cardiovascular risk factors.
Main Methods:
- Open prospective study involving 20 outpatients.
- Treatment administered: ginkgo biloba extract (EGb 761), 240 mg daily for 12 weeks.
Main Results:
- Significant improvement observed in fibrinogen levels.
- Demonstrated enhancement of hemorrheological properties.
- EGb 761 positively influenced cardiovascular risk factors.
Conclusions:
- Ginkgo biloba extract (EGb 761) is effective in improving fibrinogen levels and hemorrheological parameters.
- Long-term treatment with EGb 761 shows potential in managing cardiovascular risk factors.
- Further research into EGb 761 for cardiovascular health is warranted.
Study Design:
Open prospective study.
Patients:
20 outpatients with a long history of elevated fibrinogen levels and plasma viscosity, and a variety of underlying diseases.
Intervention:
Treatment with the special ginkgo biloba extract (EGb 761), 240 mg tablets a day for a period of 12 weeks.
Results:
The clinical diagnoses included coronary heart disease, hypertension, hypercholesterolemia and diabetes mellitus. A significant improvement in the fibrinogen levels and hemorrheological properties was seen. The medication can thus positively influence these cardiovascular risk factors over the long term.