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Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice
Published on: April 3, 2011
ATM promoter analysis in childhood lymphoid malignancies: a brief communication
Fabienne Gumy-Pause1, Pierre Wacker, Philippe Maillet
1Department of Pediatrics, Unit of Hematology/Oncology, University Hospital of Geneva, Switzerland. fabienne.gumypause@medecine.unige.ch
Leukemia Research
|August 30, 2005
Abstract:
ATM promoter hypermethylation has been recently reported in adult carcinomas, but no information is available concerning the methylation status of ATM gene promoter in childhood B-precursor acute lymphoblastic leukaemia (ALL). Furthermore, involvement of somatic ATM promoter mutations in cancer is not known. We report a complete ATM gene promoter analysis in 74 childhood lymphoid malignancies.
