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Updated: Aug 12, 2026

The Development of Lyophilized Loop-mediated Isothermal Amplification Reagents for the Detection of Coxiella burnetii
Published on: April 18, 2016
Ongoing queries: Interpretation of serology in asymptomatic or atypical chronic Q fever
T de Silva1, A Chapman, G Kudesia
1Department of Infection and Tropical Medicine, Royal Hallamshire Hospital, Sheffield, UK. thushandesilva@hotmail.com
Abstract:
Chronic Q fever, predominantly associated with endocarditis, can develop insidiously. Although the diagnosis may be straightforward with a typical clinical presentation, incidental discovery of positive Coxiella burnetii serology poses a difficult clinical challenge. We describe the cases of two such patients and review the literature on the serological diagnosis of chronic Q fever.
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