Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Genetics of asthma.

I Hall1

  • 1Department of Therapeutics, University Hospital, Nottingham, United Kingdom. ian.hall@nottingham.ac.uk

Idrugs : the Investigational Drugs Journal
|August 30, 2005
PubMed
Summary

Pharmacogenomic and pharmacogenetic research explores asthma genetics and novel therapeutic targets. Gene variations significantly impact individual responses to asthma treatments, including anti-immunoglobulin E (IgE) and anti-cytokine therapies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"A combination of everything": a mixed-methods approach to the factors which autistic people consider important in suicidality.

Autism in adulthood : challenges and management·2025
Same author

COVID-19 testing in outbreak-free care homes: what are the public health benefits?

The Journal of hospital infection·2021
Same author

A systematic review of infectious illness Presenteeism: prevalence, reasons and risk factors.

BMC public health·2019
Same author

Analysis of individual patient data to describe the incubation period distribution of Shiga-toxin producing Escherichia coli.

Epidemiology and infection·2019
Same author

A systematic review and meta-analysis on the incubation period of Campylobacteriosis.

Epidemiology and infection·2017
Same author

Barrow-in-Furness: a large community legionellosis outbreak in the UK.

Epidemiology and infection·2013

Area of Science:

  • Pharmacogenomics and genetics in respiratory medicine.

Background:

  • Asthma genetics research is rapidly evolving.
  • Understanding genetic factors is crucial for personalized asthma treatment.

Purpose of the Study:

  • To review pharmacogenomic and pharmacogenetic issues in asthma.
  • To explore novel therapeutic targets and gene variability's impact on treatment response.

Main Methods:

  • Discussion of array-based technologies for target identification.
  • Examination of signal transduction pathways and kinase targets.
  • Review of anti-immunoglobulin E (IgE) and anti-cytokine therapies.

Main Results:

  • Variability in genes coding for drug targets likely explains inter-individual differences in treatment response.
  • Novel targets may be identified through advanced genetic technologies.
  • Current and future treatment strategies are influenced by genetic insights.

Conclusions:

  • Pharmacogenomics offers a promising avenue for advancing asthma management.
  • Genetic variations are key determinants of therapeutic efficacy in asthma.
  • Further research into asthma genetics will refine treatment strategies.

Related Experiment Videos