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Ortner syndrome and haemophilia
C Hermans1, S Manocha, J E McLaughlin
1Department of Haematology, Haemostasis and Thrombosis Unit, Cliniques universitaires Saint-Luc, Catholic University of Louvain, Brussels, Belgium. hermans@sang.ucl.ac.be
Haemophilia : the Official Journal of the World Federation of Hemophilia
|September 1, 2005
Summary
Pulmonary hypertension can cause vocal cord paralysis in HIV patients. Doctors should consider HIV-associated pulmonary hypertension in HIV-infected individuals with unexplained hoarseness or vocal cord palsy.
Area of Science:
- Cardiology
- Neurology
- Infectious Diseases
Background:
- Pulmonary hypertension is a condition characterized by high blood pressure in the arteries of the lungs.
- Compression of the recurrent laryngeal nerve by a dilated pulmonary artery can lead to vocal cord paralysis.
- This is a rare complication, particularly in the context of Human Immunodeficiency Virus (HIV) infection.
Observation:
- A case report details a patient with severe hemophilia A and HIV infection.
- The patient presented with persistent hoarseness and left vocal cord palsy.
- The symptoms were attributed to HIV-associated pulmonary hypertension.
Findings:
- The dilated pulmonary artery in this HIV-positive patient compressed the left recurrent laryngeal nerve.
- This compression resulted in vocal cord paralysis, causing the patient's hoarseness.
- HIV-associated pulmonary hypertension was identified as the underlying cause.
Implications:
- This case highlights a rare but significant neurological complication of HIV-associated pulmonary hypertension.
- It suggests that unexplained vocal cord palsy in HIV patients may indicate underlying pulmonary hypertension.
- Clinicians should consider screening HIV patients with vocal cord abnormalities for pulmonary hypertension.
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