Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Orbitofrontal cortex, associative learning, and expectancies.

Geoffrey Schoenbaum1, Matthew Roesch

  • 1Department of Anatomy and Neurobiology, University of Maryland School of Medicine, 20 Penn Street, HSF-2 S251, Baltimore, Maryland 21201, USA. schoenbg@schoenbaumlab.org

Neuron
|September 1, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The oracle and the didact: Orbitofrontal influences on learning and dopaminergic error signaling.

Neuron·2026
Same author

Prior cocaine use disrupts identification of hidden states by single units and neural ensembles in orbitofrontal cortex.

eLife·2026
Same author

Persistent representation of a prior schema in the orbitofrontal cortex facilitates learning of a conflicting schema.

Nature communications·2026
Same author

Generation and characterization of a tamoxifen-inducible, Cre driver rat for transgene expression in microglia.

Scientific reports·2025
Same author

Distinct contributions of anterior and posterior orbitofrontal cortex to outcome-guided behavior.

bioRxiv : the preprint server for biology·2025
Same author

Distinct contributions of anterior and posterior orbitofrontal cortex to outcome-guided behavior.

Current biology : CB·2025
Same journal

Dynamic coordination and segregation mechanisms in higher cortex for parallel task processing.

Neuron·2026
Same journal

Higher-order thalamic bursts are drivers of attention control.

Neuron·2026
Same journal

Composing trajectories for rapid inference of navigational goals.

Neuron·2026
Same journal

Peri-head distance coding in the mouse brainstem.

Neuron·2026
Same journal

A two-timepoint framework for sensitive and specific single-cell activity screening.

Neuron·2026
Same journal

From first impressions to bonds: The neural dynamics of social relationships.

Neuron·2026
See all related articles

The orbitofrontal cortex (OFC) is crucial for controlling behavior by integrating learned associations with internal states. This brain region signals the value of potential outcomes, guiding decision-making.

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Behavioral Neuroscience

Background:

  • The orbitofrontal cortex (OFC) exhibits unique connectivity with subcortical regions like the basolateral amygdala.
  • Understanding the distinct roles of these areas in learning and behavior is essential.

Purpose of the Study:

  • To differentiate the roles of the OFC and basolateral amygdala in associative learning and behavioral control.
  • To elucidate the OFC's function in signaling the desirability of outcomes.

Main Methods:

  • This study likely involved analyzing neural pathways and functional roles through neuroscientific techniques (specific methods not detailed in the abstract).

Main Results:

  • The OFC plays a pivotal role in manipulating learned information to guide behavior.

Related Experiment Videos

  • The OFC's function involves integrating associative learning with internal states and goals.
  • Conclusions:

    • The OFC's ability to signal outcome desirability is key to its role in behavioral control.
    • Representational memory within the OFC integrates diverse information for decision-making.