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Updated: Aug 16, 2026

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
Published on: June 10, 2025
[A case of cutaneous vasculitis in a patient with systemic lupus erythematosus]
Krzysztof Mastej1, Maria Knapik-Kordecka, Rajmund Adamiec
1Katedra i Klinika Angiologii, Nadciśnienia Tetniczego i Diabetologii AM we Wrocławiu.
Abstract:
We present case of 55 years old female with systemic lupus erythematosus (SLE) and necrotic ulcerations in lower limbs. Etiology of this lesions was complex. In the presented case, vasculitis (microvasculitis) accompanying systemic inflammatory connective tissue disease coincides with deficiency of protein S and venous insufficiency lower limbs. It could determine necrotic type of ulcerations and location of lesions. In this case vasculitis was crucial importance and ulcerations were healed after immunosuppressive therapy. In similar cases it is often difficult to find factors responsible for development of ulcerations and it need different investigations. But detailed determine of etiopathogenesis gives guarantee therapeutic success.
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