Calibration of detector responses using the shape and size of band profiles. Case of a nonlinear response curve
Related Experiment Video
Updated: Aug 16, 2026

08:12
Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
Published on: March 13, 2013
Leonid Asnin1, Georges Guiochon
1Department of Chemistry, University of Tennessee, Knoxville, TN 37996-1600, USA.
Journal of Chromatography. A
|September 1, 2005
Abstract:
A new method consisting of using band profiles to calibrate the response of a detector, without making frontal analysis measurements, is discussed. A model for the calibration-curve expression is proposed. It is convenient and reasonably accurate even when the detector response deviates slightly from linear behavior at low concentrations.
More Related Videos
Related Concept Videos
Calibration Curves: Linear Least Squares
A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
For data that follow a straight line, the standard method for fitting is the linear...
For data that follow a straight line, the standard method for fitting is the linear...
Instrument Calibration
Instrument calibration is essential for ensuring that instruments produce accurate and consistent results. It is vital in manufacturing, healthcare, testing laboratories, and scientific research. Calibration processes are specific to each instrument and help enhance data accuracy. Each instrument has a unique calibration process tailored to its design and function to improve data accuracy.
Analytical Balance Calibration
An analytical balance measures mass and requires regular calibration to...
Analytical Balance Calibration
An analytical balance measures mass and requires regular calibration to...
Calibration Curves: Correlation Coefficient
In a linear calibration curve, there is a value called the calibration coefficient, denoted by 'r,' which measures the strength and the direction of association between two variables. The correlation coefficient value ranges from −1 to +1. A value of +1 indicates a perfect positive linear correlation, −1 denotes a perfect negative correlation, and 0 implies no correlation between the two variables. A positive correlation value establishes that as one variable increases, the other increases, and...

