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Effects of mushroom tyrosinase on anisaldehyde
Tae Joung Ha1, Sadaaki Tamura, Isao Kubo
1Department of Environmental Science, Policy, and Management, University of California, Berkeley, California 94720-3112, USA.
Abstract:
Anisaldehyde (p-methoxybenzaldehyde) was previously reported to inhibit the tyrosinase-catalyzed oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) noncompetitively as long as the enzyme activity was monitored by measuring dopachrome formation. However, anisaldehyde did not inhibit this oxidation if a longer reaction time was observed, although it suppressed the initial rate of oxidation to a certain extent. Anisaldehyde significantly suppressed the rate of enzymatic oxidation of L-tyrosine.
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