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Updated: Aug 16, 2026

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
Published on: June 13, 2019
[Carcinosarcoma of the breast: a tumour with controversial histogenesis]
Juana Teresa Santiago Pérez1, Mercedes R Pérez Vázquez, Amparo de la C Rivera Valdespino
1Hospital Clínico Quirúrgico Docente Dr. Salvador Allende, Ciudad de la Habana, Cuba. teresasp@infomed.sld.cu
Abstract:
Carcinosarcoma of the breast is a rare, biphasic, tumour with epithelium and mesenchymal components. Its histogenesis is controversial and, hence, has received various different nomenclatures. At present, all studies indicate that it is a variety of methaplasic tumour and suggest multi-potential myoepithelial cell origin. Clinically, it presents as a tumour of variable size and its diagnosis has been by immunohistochemistry studies, or by electron microscopy. We present, here, a patient with mammary carcinosarcoma a difficult diagnosis. Treatment for the patient was a modified radical mastectomy, and adjuvant therapy.
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