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Related Experiment Videos

Recurrence and bleeding in hibernomas.

Christian M Ogilvie1, Jesse T Torbert, Harish S Hosalkar

  • 1Pennsylvania Hospital, Philadelphia, PA 19106-6192, USA.

Clinical Orthopaedics and Related Research
|September 1, 2005
PubMed
Summary

Recurrent hibernomas can be managed with marginal excision, which prevents recurrence. Hibernomas may also cause significant bleeding during surgery, regardless of typical histology.

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Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Hibernomas, rare benign brown fat tumors, can recur and cause significant bleeding.
  • Limited clinical data exists regarding hibernoma recurrence and bleeding risk.
  • Distinguishing hibernomas from lipomas using MRI is important for diagnosis.

Purpose of the Study:

  • To investigate the relationship between resection type and hibernoma recurrence.
  • To assess the correlation between atypical histologic findings and intraoperative bleeding.
  • To confirm MRI's ability to differentiate hibernomas from lipomas.

Main Methods:

  • Retrospective review of six hibernoma cases over 10 years.
  • Analysis of surgical excision types: marginal vs. intralesional.

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  • Evaluation of histologic findings and available MRI features.

    • Main Results:

    • Two of four intralesional excisions resulted in recurrence; no marginal excisions recurred.
    • Significant bleeding occurred in two cases, unrelated to typical histology.
    • MRI in one case showed a fatty tumor distinguishable from lipoma.

    Conclusions:

    • Marginal excision appears to prevent hibernoma recurrence.
    • Hibernomas carry a risk of significant intraoperative bleeding.
    • Histology does not predict recurrence, and MRI can aid in differentiation from lipomas.