Related Experiment Video
Updated: Aug 16, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Fenestration of the Fontan circuit as treatment for plastic bronchitis
J Wilson1, J Russell, W Williams
1Department of Pediatrics, Division of Cardiology, The Hospital for Sick Children, University of Toronto School of Medicine, 555 University Avenue, Toronto, Ontario M5G1X8, Canada.
Insights
Plastic bronchitis, a rare complication after Fontan procedures, involves bronchial cast formation. Restoring fenestration in the Fontan circuit effectively resolved symptoms in a pediatric patient.
Area of Science:
- Cardiology
- Pulmonary Medicine
- Pediatric Surgery
Background:
- Plastic bronchitis is a rare, life-threatening condition characterized by bronchial cast formation, leading to pulmonary failure.
- It has been identified as a significant complication following the Fontan procedure, a complex surgery for single-ventricle congenital heart defects.
Observation:
- A 5-year-old girl, who underwent an extracardiac fenestrated Fontan repair for tricuspid atresia, developed plastic bronchitis six weeks post-surgery.
- The patient presented with airway obstruction and coughed up bronchial casts, with medical therapies showing minimal impact.
Findings:
- Cardiac catheterization to stent open the Fontan fenestration led to the resolution of plastic bronchitis symptoms.
- Recurrence of cast expectoration coincided with spontaneous closure of the stented fenestration, resolving again upon recreation of the baffle defect.
Implications:
- Fenestration within the Fontan circuit influences hemodynamics, offering a novel therapeutic approach for managing plastic bronchitis.
- This case highlights the potential of manipulating Fontan circuit hemodynamics to treat this devastating post-surgical complication.
Abstract:
Plastic bronchitis is a rare, potentially life-threatening condition in which protein casts form within and occlude the bronchus, resulting in pulmonary failure, and has been identified as a complication after the Fontan procedure. We present a case of a 5-year-old girl who had undergone an extracardiac fenestrated Fontan repair as a component of staged palliation for tricuspid atresia. Six weeks following surgery, the patient presented with airway obstruction, coughing a bronchial cast. Medical therapies to optimize heart function and attempt to control cast formation were implemented, with little clinical impact. Following cardiac catheterization to stent open the fenestration, the symptoms of plastic bronchitis resolved. Cast expectoration recurred following spontaneous closure of the stented fenestration and again resolved with recreation of the baffle defect. Fenestration of the Fontan circuit alters hemodynamics, thereby providing an additional therapeutic option for this devastating disorder.
Related Concept Videos
Chest Physiotherapy
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Mitral Stenosis III: Medical Management
COPD: Management Using Bronchodilators and Corticosteroids
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
