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Serum interleukin-11 in patients with benign prostatic hyperplasia and prostate cancer
Yuzo Furuya1, Remon Nishio, Akira Junicho
1Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan. furuyayu@med.teikyo-u.ac.jp
International Urology and Nephrology
|September 1, 2005
Abstract:
To clarify whether serum levels of interleukin-11 (IL-11) could be a useful marker in patients with prostate cancer, serum IL-11 was determined in 73 and 23 men with prostate cancer and benign prostate hyperplasia (BPH), respectively, before treatment. There were no statistical differences of IL-11 levels between patients with prostate cancer and BPH. Patients with hormone-resistant prostate cancer had a significantly higher level of IL-11 than those with untreated cancer. Serum IL-11 levels may be a potential tumor marker for prostate cancer progression.